What is one disadvantage of 2D mammography screening?

The disadvantage of 2D mammography screening that is highlighted in this context is that the glandularity of the breast can obscure cancer visualization. In 2D mammography, breast tissue can appear dense, and dense glandular tissue may hide tumors or abnormalities, making it challenging to detect cancers. This is particularly relevant for younger women or those with denser breast tissue, where the likelihood of missing a cancerous lesion increases due to the overlapping of structures in the mammogram image.

It’s important to recognize that while 2D mammography is effective for many, its limitations in visualizing cancers in denser breast tissue can lead to false negatives or delayed diagnoses, underscoring the importance of supplementary imaging techniques, such as 3D mammography, in cases where breast density is a concern.