Which breast projection is known for highlighting calcifications effectively?

The mediolateral oblique (MLO) projection is particularly effective in visualizing calcifications in breast tissue. This projection captures a significant portion of the breast's anatomy, including the upper outer quadrant, which is where most breast cancers and calcifications occur. The angling of the MLO projection allows for better differentiation of calcifications by minimizing tissue superimposition and maximizing the visualization of both glandular and adipose tissue.

Additionally, the MLO view often provides a more comprehensive assessment of breast architecture, improving the visibility of microcalcifications, which can be crucial for early detection of breast cancer. The angle of this projection also helps to maintain the integrity of the breast structure, allowing for more precise imaging that focuses on areas of interest where calcifications may reside. As a result, the MLO view is a standard technique in breast imaging protocols, especially when sensitivity to detecting subtle findings like calcifications is paramount.