Which projection improves the detail of a lesion located in the lateral aspect of the breast?

The correct choice is a projection that specifically enhances visualization of lesions in the lateral aspect of the breast. The craniocaudal (CC) view primarily offers a top-down perspective of the breast and may not provide the best angle for evaluating lesions located on the lateral side. The lateromedial (LM) view, though useful, is not typically employed for lateral lesions as effectively as the mediolateral (ML) view.

In the ML projection, the x-ray beam passes from the medial side to the lateral side of the breast, allowing for improved detail and visualization of lateral lesions. This angle effectively presents the tissue structure in a way that separates it from overlapping tissues and provides clearer diagnostic information.

The mediolateral oblique (MLO) projection, while useful for overall breast imaging, is designed to capture a broader view rather than directly focus on lesions situated lateral to the glandular tissue. Therefore, for the specific purpose of enhancing detail of a lesion located in the lateral aspect of the breast, the ML projection is by far the most effective choice, offering improved contrast and reduced tissue superimposition, facilitating better lesion characterization.