What mammographic change is likely observed in a woman after the onset of menopause who has never taken synthetic hormones?

After the onset of menopause, particularly in women who have not taken synthetic hormones, a common and expected mammographic change is signs of atrophy. This occurs due to a decrease in estrogen levels, which leads to the involution of breast tissue. As a result, there is typically a reduction in the glandular component and a corresponding increase in the fatty tissue within the breast, indicating a shift from denser glandular breast tissue to a more fatty composition.

During this phase, it is normal to see a decrease in breast size and density on mammograms, which can manifest as a softer, less dense appearance. This atrophic change is significant as it can alter the mammographic appearance of the breast, impacting both the screening and diagnostic assessment.

Understanding the changes that occur in breast tissue after menopause is crucial for interpreting mammograms accurately, as it influences the radiologist's assessment and potential recommendations for further imaging or intervention.